AFC Winter 2014 meeting

AFC Winter 2014

Held at Birkbeck College, London

January 10th 2014

Scientific Programme

Session 1

NSAIDs to tackle drug resistance in Mycobacterium tuberculosis
Arundhati Maitra, Dimitrios Evangelopoulos, Parisa Nakhostin Mortazavi, Aleksei Kovalev, Juan David Guzman, Timothy D. McHugh and Sanjib Bhakta. Mycobacteria Research Laboratory, Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck College

Structure and Function of the mycobacterial ACG protein family
Nicholas H. Keep, Francois Xavier-Chauviac, Doris Quay, James Torpey, Martin Bommer, Ambrose Cole. Institute for Structural and Molecular Biology, Crystallography, Dept of Biological Sciences, Birkbeck College

Innate and antigen-specific cytotoxic cells and paradoxical HIV-1-associated tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS)
Katalin A Wilkinson, Naomi F Walker, Graeme Meintjes, Keira H Skolimowska, Kerryn Matthews, Rebecca Tadokera, Ronnett Seldon, Gary Maartens, Mark P Nicol, Molebogeng X Rangaka, Gurdyal S. Besra, Robert J Wilkinson. Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, and MRC National Institute for Medical Research, London

High dose rifampicin therapy for a shorter treatment period
Yanmin Hu, Mitchison DA, Jindani A, Liu Y, Coates ARM. Medical Microbiology, Centre for Infection and immunity, Division of Clinical Sciences, St George’s, University of London

Getting to know Mycobacterium tuberculosis through metabolomics
Gérald Larrouy-Maumus, and Luiz Pedro Sório de Carvalho. Division of Mycobacterial Research, MRC National Institute for Medical Research, London

Session 2

Counting mycobacteria: how many beans make five?
Han Xiao, Katarina Oravcova, Wilber Sabiiti, Eoghan Farmer, Stephen Gillespie. School of Medicine, University of St.Andrews

The pathological role of neutrophil necrosis in tuberculosis
David M Lowe, Nonzwakazi Bangani, Katalin A Wilkinson, Robert J Wilkinson, Adrian R Martineau. Department of Medicine, Imperial College London, and Clinical Infectious Diseases Research Initiative, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, Cape Town, South Africa

Role of lymph node-derived lymphatic endothelial cells in mycobacterial Infection
Maximiliano G. Gutierrez. National Institute of Medical Research, Mill Hill, London

Recovery of TB genomes from metagenomes
Jacqueline Chan, Martin Sergeant, Andrew Millard, Elizabeth Wellington, Helen Donoghue and Mark Pallen. Warwick Medical School, University of Warwick

Bioelectrospray-based cell encapsulation for in vitro modelling of Mycobacterium tuberculosis induced granuloma formation
Liku B Tezera, Magda K Bielecka, Victoria Workman, Patience T Brace, Brian D Robertson, Suwan N Jayasinghe, Paul T Elkington. Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton

Programme details (Word file)

AFC Summer 2014 meeting (60th anniversary)

AFC Summer 2014

60th Anniversary meeting, Berlin

July 10-11 2014

Scientific Programme

Session 1: Berlin + Aeras Special

TB Research in Berlin Spanning 130 Years
Stefan Kaufmann, Max Planck Institute for Infection Biology

Interferons, Inflammation and Lung Injury in TB
Anca Dorhoi, MPIIB

Molecular profiling for host biomarker discovery in health and disease
Jeroen Maertzdorf, MPIIB

Individuality in disease: patient-specific and cell-specific gene expression in TB
January Weiner, MPIIB

Session 2: Offered papers

Metabolic models of mycobacteria: systems insights into pathogenesis
Johnjoe McFadden, University of Surrey

Transcriptome analysis reveals differential innate immune response of bovine macrophages to strains of the Mycobacterium tuberculosis complex
Kevin Rue-Albrecht, David A. Magee, Kevin M. Conlon, Nicolas C. Nalpas, John A. Browne, Paul A. McGettigan, Claire Healy, Kirsten E. McLoughlin, Eamonn Gormley, David E. MacHugh and Stephen V. Gordon, University College Dublin

Tetrahydrobiopterin production by macrophages is not required for protective immunity to Mycobacterium tuberculosis
Elena Stylianou, Eileen McNeill, Rachel Kandt, Keith Channon, Helen McShane, The Jenner Institute, University of Oxford

A brief history of the Acid Fast Club
Ann Rawkins, Public Health England, Porton Down

Session 3: Offered papers

Degradosome as one of the major RNA processing complexes in mycobacteria
Przemyslaw Plocinski, Maria Macios, Emilia Niemiec, Joanna Houghton, Douglas Young and Andrzej Dziembowski, Institute of Biochemistry and Biophysics Polish Academy of Sciences

NO biomarker for TB –  Expired nitric oxide and lipid body content of tubercle bacilli in sputum
Baye Gelaw, Natalie J. Garton, Gashaw Mesele,Tadye Abeje, Salie Ayalew, Pranabashis Haldar, Abraham Assefa, and Michael R Barer, Department of Medical Microbiology, CMHS, UOG, Ethiopia

Whole genome sequencing of Mycobacterium tuberculosis from sputum: a revolution in diagnostic microbiology
Amanda Claire Brown and members of the PathSeek project consortium, Oxford Gene Technology

Characterisation of host genetic factors that influence pathogen-host interplay during Mycobacterium tuberculosis infection
K. M. Kreutzfeldt, L. Mullen, C. Finan, S. J. Waddell, A. Marchant, M. J. Newportand S. M. Sacre, Brighton & Sussex Medical School, University of Sussex

The use of gene expression profiling in Mycobacterium tuberculosis as a tool to study drug efficacy and action
Dimitrios Evangelopoulos, Aidan Hanrath,Iva Treveska, Magdalena Karlikowska, Isobella Honeyborne, Sanjib Bhakta, Simon Waddel, Philip Butcherand Timothy D. McHugh, Centre for Clinical Microbiology, Royal Free Campus, University College London

Session 4: Offered papers

Development of a BCG challenge model for the testing of vaccine candidates against bovine tuberculosis
Villarreal-Ramos, B., Berg, S., Chamberlain, L., McShane, H., Hewinson, R. G., Clifford, D., Vordermeier, M., Bovine TB Group, AHVLA, Weybridge, New Haw, Surrey

Metabolite-Regulated Shutdown of Efflux Pumps is Critical for Mycobacterial Survival in Non-Permissive Growth Conditions
Obolbek Turapov, Simon J Waddell, Asel Sarybaeva, Bernard Burke, Sarah Glenn, Griselda Tudo, Gilles Labesse, Danielle I. Young, Michael YoungPeter W. Andrew, Philip D. Butcher, Martin Cohen-Gonsaud,Galina V. Mukamolova, Department of Infection, Immunity and Inflammation, University of Leicester

Redefining the mechanism of action of D-cycloserine in Mycobacterium tuberculosis
Gareth A. Prosser, Luiz Pedro Carvalho, National Institute for Medical Research, The Ridgeway, Mill Hill, London

AZALEP A randomized controlled trial of azathioprine to treat leprosy nerve damage and reactions in India: main findings
Lockwood DNJ, Darlong J, Pichimani G, Royce KK, Sundar Rao, Annamma John, London School of Hygiene & Tropical Medicine, London

A guide to killing your host cell, by Mycobacterium tuberculosis
Graham Stewart, Robert Francis, Rachel Butler, Tom Mendum, Shaza Felemban, University of Surrey

Meeting programme details Word file